Description

3-Amino-2,2,3-trimethylbutanoic acid hydrochloride is a high-purity, non-natural amino acid derivative with a sterically hindered structure. This compound is valued as a critical chiral building block and intermediate in advanced organic synthesis, particularly for introducing unique steric and electronic properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially for creating peptidomimetics and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its unique branched structure can enhance biological activity and stability.
• Peptide Chemistry: Employed as a non-proteinogenic amino acid analog to modify peptide backbones, influencing conformation, metabolic stability, and receptor binding.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Biochemical Research: Utilized in studies of enzyme inhibition, metabolic pathways, and as a tool compound in medicinal chemistry.
• Specialty Polymer Modification: Incorporated into polymers to impart specific functional groups or chiral centers for advanced material properties.

Basic Information

Product Name	3-Amino-2,2,3-trimethylbutanoic Acid Hydrochloride
CAS No.	17072-53-6
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	3-Amino-2,2,3-trimethylbutyric acid hydrochloride; 2,2,3-Trimethyl-3-aminobutanoic acid hydrochloride; 3-Amino-2,2,3-trimethyl-butyric acid hydrochloride; β-Aminopivalic acid, 3-methyl derivative hydrochloride; 3-Amino-3-methyl-2,2-dimethylpropanoic acid hydrochloride; (3-Amino-2,2,3-trimethyl-butyryl) chloride hydrochloride (common misnomer); ATBA-HCl
EINECS	Contact for details

Quality Control

Our 3-Amino-2,2,3-trimethylbutanoic acid hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.