Description

17-Hydroxy-3-Methoxyestra-2,5(10)-Diene-17-Carbonitrile is a high-purity steroidal nitrile compound that serves as a critical advanced intermediate in organic synthesis. Its precise molecular structure makes it an essential building block for the research and development of complex pharmaceutical agents and fine chemicals. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research Chemical: Used in academic and industrial laboratories for studying steroid receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules with potential biological activity.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for target molecules in pilot plants.
• Reference Standard: Can be used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	17-Hydroxy-3-Methoxyestra-2,5(10)-Diene-17-Carbonitrile
CAS No.	17006-17-6
Molecular Formula	C₂₁H₂₇NO₂
Molecular Weight	325.45 g/mol
Synonyms	17-Cyano-3-methoxyestra-2,5(10)-dien-17-ol; 3-Methoxy-17-cyanoestra-2,5(10)-dien-17-ol; 17-Hydroxy-3-methoxyestra-2,5(10)-diene-17-carbonitrile; Estra-2,5(10)-diene-17-carbonitrile, 17-hydroxy-3-methoxy-; 17-Cyano-3-methoxyestra-2,5(10)-dien-17β-ol (if applicable); 3-Methoxy-19-norpregna-2,5(10)-diene-17-carbonitrile-17-ol
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-3-Methoxyestra-2,5(10)-Diene-17-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.