Description

Boc-Cys(Et)-Oh CAS NO 16947-82-3 is a protected cysteine derivative, specifically S-ethylthio-L-cysteine with a tert-butoxycarbonyl (Boc) group on the α-amino function. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering orthogonal protection strategies essential for solid-phase and solution-phase peptide chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of bioactive peptides, and chemical biology studies.

Application

• Peptide Synthesis: A key intermediate for the controlled incorporation of cysteine residues with protected thiol functionality.
• Pharmaceutical Research: Used in the development of peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Chemical Biology: Serves as a precursor for synthesizing probes and conjugates to study protein-protein interactions and labeling.
• Bioconjugation: The protected thiol group allows for selective deprotection and subsequent conjugation to other molecules or surfaces.
• Material Science: Can be used in the synthesis of specialized polymers and biomaterials with specific thiol-reactive sites.

Basic Information

Product Name	Boc-Cys(Et)-Oh
CAS No.	16947-82-3
Molecular Formula	C₁₀H₁₉NO₄S
Molecular Weight	249.33 g/mol
Synonyms	(2R)-2-[(tert-Butoxycarbonyl)amino]-3-(ethylsulfanyl)propanoic acid; N-(tert-Butoxycarbonyl)-S-ethyl-L-cysteine; Boc-S-ethyl-L-cysteine; Boc-L-Cys(Et)-OH; Boc-Cys(Et)-OH; N-Boc-S-ethylcysteine; S-Ethyl-N-Boc-L-cysteine; L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, S-ethyl ester
EINECS	Contact for details

Quality Control

Our Boc-Cys(Et)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Specific Rotation	-15° to -25° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.