Description

2-Bromo-2-Phenylacetaldehyde is a versatile and highly reactive brominated aromatic aldehyde building block. This compound is valued for its bifunctional reactivity, where the aldehyde and bromine groups serve as key handles for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. Its structure makes it a critical intermediate for synthesizing various heterocycles, active pharmaceutical ingredients (APIs), and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of various drug candidates, particularly those containing phenylacetic acid or phenylethylamine derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in Grignard reactions, nucleophilic substitutions, and palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce functionalized phenyl groups.
• Heterocyclic Chemistry: Serves as a precursor for the synthesis of important heterocyclic scaffolds like indoles, quinolines, and isoxazoles.
• Flavor and Fragrance Ingredient Intermediate: Used in the controlled synthesis of complex aromatic compounds for specialty applications.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional materials.

Basic Information

Product Name	2-Bromo-2-Phenylacetaldehyde
CAS No.	16927-13-2
Molecular Formula	C8H7BrO
Molecular Weight	199.05 g/mol
Synonyms	α-Bromophenylacetaldehyde; 2-Bromo-2-phenylethanal; (2-Bromo-2-phenyl)acetaldehyde; Phenacyl bromide (related); ω-Bromophenylacetaldehyde; Bromophenylacetaldehyde; NSC 406916; Phenyl(bromo)acetaldehyde
EINECS	240-989-5

Quality Control

Every batch of 2-Bromo-2-Phenylacetaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure product identity, purity, and consistency for your critical research and production processes. A Certificate of Analysis (COA) detailing specifications such as assay (by GC/HPLC), identity (IR, NMR), and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize oxidation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.