Description

4-Isoxazolecarboxylicacid,3-Chloro-5-Methyl-(8Ci,9Ci) is a high-purity heterocyclic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique isoxazole core, functionalized with chloro and methyl groups, makes it a versatile intermediate for constructing complex molecular architectures with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting anti-inflammatory, antimicrobial, or central nervous system (CNS) activities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and dyes due to its conjugated system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Isoxazolecarboxylicacid,3-Chloro-5-Methyl-(8Ci,9Ci)
CAS No.	16880-29-8
Molecular Formula	C5H4ClNO3
Molecular Weight	161.54 g/mol
Synonyms	3-Chloro-5-methyl-1,2-oxazole-4-carboxylic acid; 3-Chloro-5-methylisoxazole-4-carboxylic acid; 4-Carboxy-3-chloro-5-methylisoxazole; 3-Chloro-5-methyl-4-isoxazolecarboxylic acid; 3-Chloro-5-methyl-4-carboxyisoxazole; 16880-29-8; 3-Chloro-5-methylisoxazol-4-yl carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarboxylicacid,3-Chloro-5-Methyl-(8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.