Description

2-Hydroxy-4-Iodobenzoic Acid is a halogenated derivative of salicylic acid, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a phenolic hydroxyl and a carboxylic acid group ortho to an iodine atom, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise functionalization for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other iodine-containing therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where the iodine moiety introduces specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis, useful in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs) due to its ability to modify electronic properties.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Academic & R&D: A valuable reagent for organic synthesis research in universities and corporate R&D centers exploring new reaction pathways.

Basic Information

Product Name	2-Hydroxy-4-Iodobenzoic Acid
CAS No.	16870-28-3
Molecular Formula	C7H5IO3
Molecular Weight	263.02 g/mol
Synonyms	4-Iodosalicylic Acid; 4-Iodo-2-hydroxybenzoic Acid; 2-Hydroxy-4-iodobenzoic Acid; Salicylic Acid, 4-iodo-; Benzoic acid, 2-hydroxy-4-iodo-; 4-Iodo-2-hydroxybenzoic acid; 2-Hydroxy-4-iodobenzoic acid; 16870-28-3
EINECS	240-897-7

Quality Control

Our 2-Hydroxy-4-Iodobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents. We support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	215°C - 220°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.