Description

2-Hydroxy-6-Nitrobenzaldehyde is a versatile aromatic aldehyde derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a nitro group ortho to the aldehyde, makes it a valuable building block for constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with benzofuran, quinoline, or other fused heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators where its nitro and aldehyde functionalities enable further chemical modifications.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and other complex colorants, leveraging its ability to form Schiff bases and undergo condensation reactions.
• Ligand and Chelating Agent Precursor: The ortho-hydroxyaldehyde structure is ideal for synthesizing bidentate ligands used in catalysis and metal complexation.
• Organic Electronic Materials: Investigated as a building block for novel organic semiconductors and photoactive materials due to its electron-withdrawing nitro group.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Hydroxy-6-Nitrobenzaldehyde
CAS No.	16855-08-6
Molecular Formula	C7H5NO4
Molecular Weight	167.12 g/mol
Synonyms	6-Nitrosalicylaldehyde; 2-Hydroxy-6-nitrobenzaldehyde; 6-Nitro-2-hydroxybenzaldehyde; Salicylaldehyde, 6-nitro-; 6-Nitrosalicylaldehyde; 2-Formyl-3-nitrophenol; 3-Nitro-2-hydroxybenzaldehyde
EINECS	240-876-8

Quality Control

Our 2-Hydroxy-6-Nitrobenzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.