Description

(2R)-3,4-Dihydro-2-(4-Hydroxyphenyl)-2H-1-Benzopyran-3α,4β,7,8-Tetrol CAS NO 16854-91-4 is a high-purity, stereochemically defined benzopyran derivative, a key chiral intermediate and reference standard for advanced research and development. This compound matters for its role in the synthesis of complex natural products and bioactive molecules, offering precise structural control. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry, natural product synthesis, and analytical method development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical chemistry for method validation, quality control, and identification in HPLC, LC-MS, and NMR.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Natural Product Synthesis: A key intermediate in the total or semi-synthesis of complex flavonoids and related natural compounds.
• Biochemical Research: Investigated for its potential biological activities and interactions with various enzyme systems.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Item	Details
Product Name	(2R)-3,4-Dihydro-2-(4-Hydroxyphenyl)-2H-1-Benzopyran-3α,4β,7,8-Tetrol
CAS No.	16854-91-4
Molecular Formula	C15H14O6
Molecular Weight	290.27 g/mol
Synonyms	(2R)-Taxifolin; (2R)-Dihydroquercetin; (2R,3R)-Dihydroquercetin; (2R,3R)-Taxifolin; (2R)-3,3',4',5,7-Pentahydroxyflavanone; Distylin; (+)-Taxifolin; (+)-Dihydroquercetin; Larixinol
EINECS	Contact for details

Quality Control

Every batch of (2R)-3,4-Dihydro-2-(4-Hydroxyphenyl)-2H-1-Benzopyran-3α,4β,7,8-Tetrol is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (including HPLC purity and chiral purity) are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2R,3R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.