Description

n-(p-Toluenesulfonyl)-3-Pyrroline is a versatile heterocyclic building block and sulfonamide derivative of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex nitrogen-containing molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of pyrrolidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the pyrroline scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized nitrogen-donor ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the sulfonamide group modifies solubility and electronic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in ring-forming reactions and sulfonylation chemistry.

Basic Information

Product Name	n-(p-Toluenesulfonyl)-3-Pyrroline
CAS No.	16851-72-2
Molecular Formula	C11H13NO2S
Molecular Weight	223.29 g/mol
Synonyms	1-Tosyl-3-pyrroline; 1-(4-Methylphenyl)sulfonyl-2,5-dihydro-1H-pyrrole; 3-Pyrroline, 1-(p-tolylsulfonyl)-; N-Tosyl-3-pyrroline; 1-(Toluene-4-sulfonyl)-2,5-dihydro-1H-pyrrole; 2,5-Dihydro-1H-pyrrole-1-sulfonic acid p-tolyl ester; N-(4-Methylbenzenesulfonyl)-2,5-dihydropyrrole
EINECS	Contact for details

Quality Control

Our n-(p-Toluenesulfonyl)-3-Pyrroline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.