Description

Alane-Trimethylamine Complex is a versatile and highly reactive organoaluminum reagent, widely used as a selective reducing agent and hydride source in organic synthesis. Its primary value lies in its ability to facilitate challenging reductions under mild conditions, offering chemists a powerful tool for constructing complex molecular architectures. This complex is particularly essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over stereochemistry and functional group transformation is critical.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the stereoselective reduction of ketones, aldehydes, and imines in the production of active pharmaceutical ingredients (APIs).
• Asymmetric Hydrogenation Catalyst Precursor: Serves as a hydride source in the preparation of catalysts for enantioselective hydrogenation reactions.
• Polymerization Co-catalyst: Used in Ziegler-Natta type polymerization systems and as an activator for olefin polymerization catalysts.
• Fine Chemical Manufacturing: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring high-purity reduction steps.
• Hydroalumination Reactions: Facilitates the addition of Al-H bonds across carbon-carbon multiple bonds (alkynes, alkenes) for carbon chain elongation and functionalization.
• Regioselective Reductions: Useful for the chemoselective reduction of specific functional groups in multifunctional molecules.

Basic Information

Product Name	Alane-Trimethylamine Complex
CAS No.	16842-00-5
Molecular Formula	C₃H₁₂AlN
Molecular Weight	89.12 g/mol
Synonyms	Aluminum Hydride Trimethylamine Complex; Trimethylamine-Alane Complex; Alane NMe3 Adduct; Trimethylamine Alane; AlH3·N(CH3)3; Aluminum Hydride-TMA Complex; TMA-Alane; (Trimethylamine)trihydroaluminum
EINECS	240-877-9

Quality Control

Our Alane-Trimethylamine Complex is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and active hydride content. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment. Our quality management system supports compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) and handled in a glovebox or under strict anhydrous conditions to prevent decomposition and maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (AlH₃ content)	≥ 95.0 %
Trimethylamine Content	Balance
Solubility	Soluble in aromatic and ether solvents (e.g., toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.