Description

2,2,5-Trimethyl-1,3-Dioxane-5-Carboxylic Acid is a specialized organic compound featuring a dioxane ring structure with a carboxylic acid functional group. This unique molecular architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with specific stereochemistry and functionality. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical research and development teams for the production of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to biological activity and selectivity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemical configurations.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Academic & Industrial Research: Employed as a model compound or starting material in methodological development and catalysis studies.
• Ligand and Catalyst Development: Its functional groups make it a candidate for constructing complex ligands used in asymmetric catalysis.

Basic Information

Item	Detail
Product Name	2,2,5-Trimethyl-1,3-Dioxane-5-Carboxylic Acid
CAS No.	16837-14-2
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	5-Carboxy-2,2,5-trimethyl-1,3-dioxane; 1,3-Dioxane-5-carboxylic acid, 2,2,5-trimethyl-; Trimethyl dioxane carboxylic acid; 2,2,5-Trimethyl-1,3-dioxane-5-carboxylic acid; NSC 163045; 5-Carboxy-2,2,5-trimethyl-m-dioxane
EINECS	240-876-6

Quality Control

Our 2,2,5-Trimethyl-1,3-Dioxane-5-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.