Description

(S)-5-Amino-2-Hydroxypentanoic Acid is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral building block for the construction of complex molecules, particularly in pharmaceutical research and development. Industries that need it include pharmaceutical companies, biotechnology firms, and fine chemical manufacturers engaged in the synthesis of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds. Its specific stereochemistry provides a critical handle for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of novel drug candidates, particularly for protease inhibitors and other enzyme-targeted therapies.
• Peptide Synthesis: Used as a specialized amino acid residue in the solid-phase or solution-phase synthesis of modified peptides with enhanced stability or biological properties.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme-substrate interaction research.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Prodrug Development: Utilized in the design of prodrugs where its amino and carboxylic acid functionalities allow for targeted release mechanisms.
• Chemical Biology Tool: Incorporated into molecular probes to study protein function and cellular processes.

Basic Information

Product Name	(S)-5-Amino-2-Hydroxypentanoic Acid
CAS No.	16814-81-6
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S)-5-Amino-2-hydroxypentanoic acid; L-2-Hydroxy-5-aminopentanoic acid; (S)-2-Hydroxy-5-aminovaleric acid; 5-Amino-2-hydroxyvaleric acid; (S)-Homo-β-hydroxyornithine; 2-Hydroxy-5-aminopentanoic acid; (S)-5-Amino-2-hydroxyvaleric acid; (2S)-2-Hydroxy-5-aminopentanoic acid
EINECS	Contact for details

Quality Control

Our (S)-5-Amino-2-Hydroxypentanoic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality control includes comprehensive analytical testing such as chiral HPLC for enantiomeric purity, NMR for structural confirmation, and titration for assay determination. We provide full traceability and Certificates of Analysis (COA) are available for every batch, detailing all critical specifications. Our commitment is to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.