Description

4-(Acetylamino)-2-Methoxybenzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its ability to act as a versatile building block for introducing the sulfonamide moiety, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly those developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those containing sulfonamide groups, such as enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonamide functionality contributes to efficacy and selectivity.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for producing specialty dyes and organic pigments, leveraging its aromatic and reactive sulfonyl chloride group.
• Polymer Modification: Employed to introduce functional sulfonamide groups into polymer chains, altering properties like solubility, thermal stability, or biocompatibility.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new synthetic routes and creating compound libraries for screening.
• Liquid Crystal and OLED Material Production: Used in the synthesis of advanced organic electronic materials where specific molecular architecture is required.

Basic Information

Product Name	4-(Acetylamino)-2-Methoxybenzenesulfonyl Chloride
CAS No.	16781-12-7
Molecular Formula	C9H10ClNO4S
Molecular Weight	263.70 g/mol
Synonyms	N-Acetyl-2-methoxy-4-aminobenzenesulfonyl chloride; 4-Acetamido-2-methoxybenzenesulfonyl chloride; 2-Methoxy-4-acetamidobenzenesulfonyl chloride; 4-(Acetylamino)-2-methoxybenzenesulfonyl chloride; 4-Acetamido-2-methoxybenzene-1-sulfonyl chloride; p-Acetamido-o-methoxybenzenesulfonyl chloride; 4-Acetylamino-2-methoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-(Acetylamino)-2-Methoxybenzenesulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and high industry standards. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.