Description

4-Chloro-1,2-Dimethoxy-Benzene is a versatile halogenated aromatic ether compound, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized benzene core with orthogonal reactivity, enabling precise chemical modifications. This intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to construct complex molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring a substituted dimethoxybenzene scaffold.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and other crop protection agents where the chloro and methoxy groups impart specific bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create more complex aromatic systems.
• Dye and Pigment Precursor: Serves as a starting material for synthesizing specialized dyes and organic pigments.
• Liquid Crystal & Electronic Materials: A potential intermediate in the synthesis of organic semiconductors and liquid crystal display (LCD) components.
• Flavor & Fragrance Chemistry: Used in the research and synthesis of certain aromatic compounds for specialty applications.

Basic Information

Product Name	4-Chloro-1,2-Dimethoxy-Benzene
CAS No.	16766-27-1
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	1-Chloro-3,4-dimethoxybenzene; 4-Chloroveratrole; 3,4-Dimethoxychlorobenzene; Veratrole, 4-chloro-; 3,4-Dimethoxy-1-chlorobenzene; 4-Chloro-1,2-dimethoxybenzene; 1,2-Dimethoxy-4-chlorobenzene; NSC 406913
EINECS	240-816-6

Quality Control

Our 4-Chloro-1,2-Dimethoxy-Benzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.