Description

3-Hydroxyasparagine is a non-proteinogenic amino acid derivative of asparagine, featuring an additional hydroxyl group on the β-carbon. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and biochemical research. It is particularly relevant for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel bioactive compounds, peptide mimetics, and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for metabolic and neurological targets.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a substrate analog in biochemical assays.
• Peptide Chemistry: Incorporated into synthetic peptides to study structure-activity relationships (SAR) and to modulate peptide stability, solubility, and biological activity.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthesis of complex natural products, custom amino acids, and other high-value organic molecules.
• Nutritional Science Research: Investigated for its potential role and effects in amino acid metabolism and related nutritional studies.

Basic Information

Product Name	3-Hydroxyasparagine
CAS No.	16712-79-1
Molecular Formula	C4H8N2O4
Molecular Weight	148.12 g/mol
Synonyms	3-Hydroxy-L-asparagine; L-erythro-3-Hydroxyasparagine; (2S,3S)-2-Amino-3-hydroxybutanedioic acid diamide; β-Hydroxyasparagine; Hya; 3-Hydroxyaspartic acid diamide; 3-OH-Asn
EINECS	Contact for details

Quality Control

Our 3-Hydroxyasparagine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.