Description

4-Bromo-2-Thiophenecarboxylic Acid is a high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceuticals, agrochemicals, and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a precursor for conductive polymers, organic semiconductors, and liquid crystals due to the electron-rich thiophene ring.
• Chemical Synthesis: Employed in Suzuki, Stille, and other cross-coupling reactions to introduce the 2-thiophene moiety into more complex molecules.
• Ligand and Catalyst Development: Utilized for creating novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-2-Thiophenecarboxylic Acid
CAS No.	16694-18-1
Molecular Formula	C5H3BrO2S
Molecular Weight	206.04 g/mol
Synonyms	4-Bromo-2-thiophenecarboxylic acid; 4-Bromothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-bromo-; 4-Bromo-2-carboxythiophene; 4-Bromothiophene-2-carboxylic acid; 4-Bromothiophene-2-carboxylic acid (9CI); 4-Bromo-2-thiophenecarboxylic acid (ACD/Name 4.0); 4-Bromothiophene-2-carboxylic acid, 4-Bromo-2-thiophenecarboxylic acid
EINECS	240-755-8

Quality Control

Our 4-Bromo-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.