Description

2-(3-Chloropropyl)-1,3-Dioxolane is a versatile chlorinated acetal derivative, serving as a key protected aldehyde intermediate and a valuable building block in organic synthesis. Its primary commercial value lies in its bifunctional reactivity, where the chloropropyl moiety enables alkylation or further functionalization while the dioxolane group protects a carbonyl, allowing for selective synthetic transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a masked aldehyde functionality for stepwise synthesis.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chloropropyl chain is incorporated into the final molecule.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent in specialty polymers, imparting specific chemical resistance or physical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for the preparation of aldehydes, ketones, and other heterocyclic compounds via deprotection and subsequent reactions.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing complex ligands used in catalytic systems for asymmetric synthesis.
• Flavor & Fragrance Industry: Intermediate in the multi-step synthesis of certain aroma chemicals and flavor compounds.

Basic Information

Product Name	2-(3-Chloropropyl)-1,3-Dioxolane
CAS No.	16686-11-6
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	3-Chloropropyl Ethylene Acetal; 1,3-Dioxolane, 2-(3-chloropropyl)-; 3-Chloro-1-propanal Ethylene Acetal; (3-Chloropropyl)ethylene Acetal; 4-Chlorobutyraldehyde Ethylene Acetal; 2-(3-Chloropropyl)-1,3-dioxacyclopentane; 3-Chloropropanal Cyclic Ethylene Acetal
EINECS	240-737-6

Quality Control

Our 2-(3-Chloropropyl)-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at ambient temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.4400 - 1.4450
Density (20°C)	1.15 - 1.20 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.