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7-Bromo-1H-Indene CAS NO 16657-07-1


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CAS No.:16657-07-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Bromo-1H-Indene is a halogenated indene derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value proposition lies in providing a functionalized aromatic scaffold for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require precise bromination for further cross-coupling reactions or structural elaboration.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the indene core for bioactivity.
  • Material Science Precursor: Serves as a monomer or starting material for the development of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
  • Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
  • Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and transition metal complexes.
  • Chemical Research & Development: A fundamental reagent in academic and industrial labs for methodological studies and exploring new synthetic routes.

Basic Information

Product Name 7-Bromo-1H-Indene
CAS No. 16657-07-1
Molecular Formula C9H7Br
Molecular Weight 195.06 g/mol
Synonyms 7-Bromoindene; 1H-Indene, 7-bromo-; 7-Bromo-1H-indene; 7-Brominden; 7-Bromo-indene; 7-Bromoindene (6CI,7CI,8CI); NSC 406914
EINECS Contact for details

Quality Control

Our 7-Bromo-1H-Indene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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