Description

5-[(Trimethylsilyl)Oxy]Pentyl(Phenyl) Ether is a specialized organosilicon compound featuring a silyl-protected hydroxyl group and an aromatic ether linkage. This unique bifunctional structure makes it a valuable protected intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly where selective deprotection is required.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators that incorporate silicon and aromatic functionalities.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material or intermediate in the synthesis of advanced organic electronic materials and liquid crystal compounds.
• Polymer Modification: Employed to introduce silyl ether and phenyl ether groups into polymer backbones to modify thermal stability, solubility, or surface properties.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.
• Organic Synthesis Reagent: Utilized as a versatile reagent for introducing the 5-[(trimethylsilyl)oxy]pentyl chain into target molecules, offering a handle for further functionalization.

Basic Information

Product Name	5-[(Trimethylsilyl)Oxy]Pentyl(Phenyl) Ether
CAS No.	16654-53-8
Molecular Formula	C14H24O2Si
Molecular Weight	252.43 g/mol
Synonyms	5-(Trimethylsiloxy)-1-pentoxybenzene; 1-(Phenoxy)-5-(trimethylsiloxy)pentane; Pentane, 1-phenoxy-5-(trimethylsiloxy)-; (5-Phenoxypentoxy)trimethylsilane; Trimethyl[5-(phenoxy)pentoxy]silane; Phenyl 5-(trimethylsilyloxy)pentyl ether; 5-Phenoxypentyloxytrimethylsilane
EINECS	Contact for details

Quality Control

Our production of 5-[(Trimethylsilyl)Oxy]Pentyl(Phenyl) Ether adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the silyl ether group.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.