Description

(4-Methoxybutoxy)Trimethylsilane is a versatile organosilicon compound featuring a protected alkoxy functionality. This chemical is valued for its role as a key intermediate and protecting group reagent in sophisticated organic synthesis, particularly in the pharmaceutical and fine chemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialty polymers where controlled reactivity and silicon-based modifications are required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where the (4-methoxybutoxy) group serves as a protected form of a hydroxyl or other functional group.
• Silicon-Based Protecting Group: Acts as a reagent for introducing the trimethylsilyl (TMS) protecting group onto alcohols or other nucleophiles under mild conditions.
• Fine Chemical Synthesis: Serves as a building block in the production of specialty chemicals, agrochemicals, and performance materials.
• Surface Modification Agent: Can be utilized to modify the surface properties of silica, glass, or other inorganic materials, imparting hydrophobic characteristics.
• Polymer & Resin Chemistry: Employed as a monomer or cross-linking agent in the development of silicone-based polymers and hybrid organic-inorganic materials.
• Electronics & Semiconductor Industry: Potential use in chemical vapor deposition (CVD) processes or as a precursor for silicon-containing thin films.

Basic Information

Product Name	(4-Methoxybutoxy)Trimethylsilane
CAS No.	16654-44-7
Molecular Formula	C8H20O2Si
Molecular Weight	176.33 g/mol
Synonyms	1-(Trimethylsilyloxy)-4-methoxybutane; 4-Methoxybutyl Trimethylsilyl Ether; Trimethyl(4-methoxybutoxy)silane; 4-Methoxybutoxy(trimethyl)silane; Butane, 1-(trimethylsilyloxy)-4-methoxy-; (4-Methoxy-butoxy)-trimethyl-silane; TMS-Protected 4-Methoxybutanol; 4-Methoxy-1-(trimethylsiloxy)butane
EINECS	Contact for details

Quality Control

Our (4-Methoxybutoxy)Trimethylsilane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.410 - 1.420
Density (20°C)	0.85 - 0.90 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.