Description

Bicyclo[3.1.0]Hexane-6-Carboxylic Acid is a specialized bicyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique strained ring structure makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring rigid, three-dimensional scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic framework can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry in complex reactions.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored thermal or mechanical properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tools to study biological systems and enzyme mechanisms.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing unique aroma chemicals with complex, bicyclic structures.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-6-Carboxylic Acid
CAS No.	16650-37-6
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	6-Bicyclo[3.1.0]hexanecarboxylic acid; Bicyclo[3.1.0]hexane-6-carboxylic acid; 3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid (related); 6-Carboxybicyclo[3.1.0]hexane; NSC 163022; 1,5-Methano-2H-cyclopropa[a]pentalene-2-carboxylic acid, 1,3,3a,4,5,6-hexahydro- (8CI)
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.