Description

(±)-trans-2-p-Tolylcyclopropanecarboxylic Acid CAS NO 16633-44-6 is a high-purity, synthetically valuable cyclopropane derivative. This compound serves as a critical chiral building block and versatile synthetic intermediate in advanced organic synthesis. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Building block for developing novel pesticides and herbicides with specific stereochemical configurations.
• Chiral Ligand & Catalyst Development: Used in the preparation of ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing strained ring systems and studying cyclopropane chemistry.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring precise stereochemistry.
• Material Science: Potential monomer or additive for creating polymers with unique thermal or mechanical properties.

Basic Information

Product Name	(±)-trans-2-p-Tolylcyclopropanecarboxylic Acid
CAS No.	16633-44-6
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	trans-2-(4-Methylphenyl)cyclopropanecarboxylic Acid; (±)-trans-2-(p-Tolyl)cyclopropanecarboxylic Acid; 2-(4-Methylphenyl)cyclopropanecarboxylic Acid; 2-(p-Tolyl)cyclopropanecarboxylic Acid; 4-Methyl-trans-2-phenylcyclopropanecarboxylic Acid; 1,2-trans-2-(4-Methylphenyl)cyclopropanecarboxylic Acid; (1R,2S)- and (1S,2R)-2-(4-Methylphenyl)cyclopropanecarboxylic Acid (racemic mixture)
EINECS	Contact for details

Quality Control

Our (±)-trans-2-p-Tolylcyclopropanecarboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	Racemic mixture (50:50)
Trans/Cis Isomer Ratio (HPLC)	≥ 99:1 (trans)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.