Description

2-Iodo-4-Methylthiophene is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the construction of complex molecules, particularly in pharmaceutical and materials science research. It is essential for chemists and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing thiophene scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the iodine atom facilitates further functionalization.
• Material Science: Serves as a building block for conjugated polymers and organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Iodo-4-Methylthiophene
CAS No.	16488-58-7
Molecular Formula	C5H5IS
Molecular Weight	224.06 g/mol
Synonyms	4-Methyl-2-iodothiophene; 2-Iodo-4-methylthiophene; 4-Methylthiophene-2-iodide; Thiophene, 2-iodo-4-methyl-; Iodomethylthiophene
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Methylthiophene is produced and tested under a stringent quality management system to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our clients in regulated development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.