Description

5-Bromo[1,1'-Biphenyl]-2-Ol is a halogenated biphenyl derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a key building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its biphenyl core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the biphenyl unit contributes to desired electronic and structural properties.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tags used in biochemical assays and diagnostic research.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig amination, due to its reactive bromine site.

Basic Information

Product Name	5-Bromo[1,1'-Biphenyl]-2-Ol
CAS No.	16434-97-2
Molecular Formula	C₁₂H₉BrO
Molecular Weight	249.10 g/mol
Synonyms	5-Bromo-2-hydroxybiphenyl; 2-Hydroxy-5-bromobiphenyl; 5-Bromobiphenyl-2-ol; 2-Biphenylol, 5-bromo-; (1,1'-Biphenyl)-2-ol, 5-bromo-; 5-Bromo-2-phenylphenol; 2-(5-Bromophenyl)phenol; 5-Bromo-2-hydroxy-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 5-Bromo[1,1'-Biphenyl]-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specified requirements. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.