Description

2-Amino-1-(4-Nitrophenyl)Ethanol is a versatile chiral amino alcohol building block characterized by its nitro-substituted aromatic ring. This compound matters as a critical intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals, offering a handle for further functionalization. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and academic research laboratories focused on asymmetric synthesis and catalyst development.

Application

• Key chiral intermediate in the synthesis of β-blocker and other cardiovascular active pharmaceutical ingredients (APIs).
• Building block for the preparation of ligands used in asymmetric catalysis and organocatalysis.
• Precursor in agrochemical research for developing novel crop protection agents.
• Starting material for the synthesis of complex heterocyclic compounds in medicinal chemistry.
• Intermediate in dye and pigment chemistry due to the presence of the nitro and amino functional groups.
• Used in academic and industrial research for studying structure-activity relationships (SAR).

Basic Information

Product Name	2-Amino-1-(4-Nitrophenyl)Ethanol
CAS No.	16428-47-0
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	1-(4-Nitrophenyl)-2-aminoethanol; 2-Amino-1-(4-nitrophenyl)ethan-1-ol; 4-Nitro-α-(aminomethyl)benzyl alcohol; (RS)-2-Amino-1-(4-nitrophenyl)ethanol; (±)-2-Amino-1-(4-nitrophenyl)ethanol; DL-2-Amino-1-(4-nitrophenyl)ethanol; 2-Amino-2-(4-nitrophenyl)ethanol (common misnomer); Amino(4-nitrophenyl)methyl]methanol
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4-Nitrophenyl)Ethanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.