Description

2,2-Dimethylpropylmethanesulphonate is a specialized organosulfur compound, specifically a methanesulfonate ester, valued for its role as a versatile alkylating agent and synthetic intermediate in advanced organic synthesis. Its unique neopentyl-like structure imparts specific steric and electronic properties, making it crucial for constructing complex molecular architectures. This high-purity chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where precise functionalization is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 2,2-dimethylpropyl (neopentyl) moiety.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides as an alkylating agent to modify biological activity and stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced organic materials requiring specific side-chain functionalization.
• Chemical Derivatization: Acts as a reagent for protecting groups or for introducing sulfonate esters in complex multi-step synthetic pathways.
• Process Chemistry: Utilized in scale-up and optimization of manufacturing routes for fine chemicals under controlled conditions.

Basic Information

Product Name	2,2-Dimethylpropylmethanesulphonate
CAS No.	16427-42-2
Molecular Formula	C7H16O3S
Molecular Weight	180.27 g/mol
Synonyms	Neopentyl Methanesulfonate; 2,2-Dimethylpropyl Methanesulfonate; Pivalylmethyl Methanesulfonate; Methanesulfonic Acid 2,2-Dimethylpropyl Ester; 1-Methanesulfonyloxy-2,2-dimethylpropane; 2,2-Dimethyl-1-propanol Methanesulfonate; NSC 403119
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylpropylmethanesulphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent derivative, ensure containers are kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.