Description

6-Phenyl-5-Hexenoic Acid is a versatile organic intermediate featuring both a carboxylic acid and an unsaturated alkene moiety attached to a phenyl ring. This unique structure makes it a valuable building block for synthesizing more complex molecules in pharmaceutical and fine chemical research. It is particularly sought after by R&D chemists and process development scientists working in advanced organic synthesis. The compound, identified by CAS number 16424-56-9, enables the introduction of specific functional groups and carbon chain lengths into target molecules.

Application

The bifunctional nature of 6-Phenyl-5-hexenoic acid opens diverse pathways in synthetic chemistry. Its primary applications include:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a lipophilic aromatic-acid spacer.
• Liquid Crystal & OLED Material Synthesis: Used in constructing core structures for advanced electronic materials due to its rigid phenyl group and modifiable chain.
• Polymer Modification: Acts as a monomer or co-monomer for introducing phenyl groups and cross-linking sites into specialty polymers.
• Peptidomimetics & Bio-conjugation: The carboxylic acid group facilitates coupling reactions to create peptide analogs or linker molecules for bioconjugation.
• Fragrance & Flavor Chemistry: Utilized as an intermediate for synthesizing aromatic compounds with specific olfactory properties.
• Organic Synthesis Building Block: Employed in various carbon-carbon bond forming reactions, such as olefin metathesis or Michael additions, to create complex molecular architectures.

Basic Information

Product Name	6-Phenyl-5-Hexenoic Acid
CAS No.	16424-56-9
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	5-Hexenoic acid, 6-phenyl-; 6-Phenyl-5-hexenoic acid; (5-Hexenoyl)benzene; 6-Phenylhex-5-enoic acid; γ-Phenylallylacetic acid; 3-(3-Phenylprop-2-en-1-yl)propanoic acid; 4-Phenyl-3-butenylacetic acid; Benzenepentenoic acid
EINECS	Contact for details

Quality Control

Our 6-Phenyl-5-Hexenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.