Description

(Iodomethyl)Cyclobutane CAS NO 16408-62-1 is a versatile organoiodine compound featuring a cyclobutane ring substituted with an iodomethyl group. This structure makes it a valuable building block in organic synthesis, particularly for introducing the cyclobutylmethyl moiety via cross-coupling or substitution reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing strained ring systems for enhanced biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the cyclobutane scaffold.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in Negishi, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the synthesis of monomers or additives for polymers with unique thermal or mechanical properties.
• Radiolabeling Precursor: Potential starting material for the synthesis of iodine-123 or iodine-131 labeled compounds for diagnostic or research purposes.

Basic Information

Product Name	(Iodomethyl)Cyclobutane
CAS No.	16408-62-1
Molecular Formula	C5H9I
Molecular Weight	196.03 g/mol
Synonyms	Cyclobutanemethyl iodide; (Iodomethyl)cyclobutane; Cyclobutylmethyl iodide; 1-(Iodomethyl)cyclobutane; Cyclobutanemethanol, iodide; Iodomethylcyclobutane
EINECS	Contact for details

Quality Control

Our (Iodomethyl)Cyclobutane is produced under strict quality management protocols. Each batch is analyzed to ensure high chemical purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.