Description

(1S,4S)-Norborna-5-Ene-2-One is a high-purity, chiral bicyclic ketone that serves as a critical synthetic building block and chiral auxiliary in advanced organic synthesis. Its rigid, defined stereochemistry makes it invaluable for constructing complex molecular architectures with precise spatial control. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Employed as a chiral scaffold or auxiliary in Diels-Alder reactions and other cycloadditions to induce stereoselectivity.
• Agrochemical Research: Used in the development of novel herbicides and pesticides with specific stereochemical requirements for enhanced activity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers with unique thermal or mechanical properties.
• Fragrance & Flavor Chemistry: Acts as a starting material for synthesizing camphor-like and other terpenoid-based aroma chemicals.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies at universities and corporate R&D centers.

Basic Information

Product Name	(1S,4S)-Norborna-5-Ene-2-One
CAS No.	16346-63-7
Molecular Formula	C7H8O
Molecular Weight	108.14 g/mol
Synonyms	(1S,4S)-Bicyclo[2.2.1]hept-5-en-2-one; (1S,4S)-5-Norbornen-2-one; (-)-(1S,4S)-Norborn-5-ene-2-one; (1S,4S)-Norcamphor; endo-5-Norbornene-2-one; L-(-)-Norborn-5-ene-2-one; (1S,4S)-2-Norbornen-5-one
EINECS	Contact for details

Quality Control

Our (1S,4S)-Norborna-5-Ene-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	92 - 96 °C
Specific Rotation [α]20/D	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.