Description

2-Chloro-5-Methanesulfonylaniline is a high-purity, versatile aromatic amine derivative characterized by its chloro and methanesulfonyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis, enabling the creation of complex molecules with specific functionalities. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drugs, including potential candidates for enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its aniline and sulfonyl group reactivity.
• Dye and Pigment Manufacturing: Serves as a building block for producing azo dyes and other complex colorants due to its diazotizable amino group.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, such as polyamides or epoxy hardeners, to impart specific chemical resistance or thermal properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a scaffold for constructing heterocyclic compounds in medicinal chemistry research.
• Material Science Research: Investigated for use in the development of organic semiconductors, liquid crystals, and other advanced functional materials.

Basic Information

Product Name	2-Chloro-5-Methanesulfonylaniline
CAS No.	16328-56-6
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	2-Chloro-5-(methylsulfonyl)aniline; 5-Amino-2-chlorophenyl methyl sulfone; Benzenamine, 2-chloro-5-(methylsulfonyl)-; 2-Chloro-5-methanesulphonylaniline; 2-Chloro-5-methylsulfonylaniline; 2-Chloro-5-(methanesulfonyl)phenylamine; 5-(Methylsulfonyl)-2-chloroaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methanesulfonylaniline is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting customer and research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.