Description

(S)-5-Hexanolide is a high-purity chiral lactone, a key building block in advanced organic synthesis. Its defined stereochemistry is critical for producing enantiomerically pure compounds with specific biological activities. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A versatile chiral synthon for the synthesis of enantiomerically pure drugs and bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry affects efficacy and environmental profile.
• Flavor and Fragrance Ingredient: Serves as a precursor for lactone-based aroma compounds, contributing to creamy, fruity, or coconut-like notes.
• Polymer Chemistry: Acts as a monomer or co-monomer for the synthesis of biodegradable polyesters and specialty polymers.
• Asymmetric Catalysis Research: A valuable substrate for developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in multi-step syntheses of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	(S)-5-Hexanolide
CAS No.	16320-13-1
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(S)-δ-Hexalactone; (S)-5-Hydroxyhexanoic acid lactone; (S)-Hexan-5-olide; (S)-Tetrahydro-2H-pyran-2-one; (S)-5-Methylvalerolactone; (S)-5-Methyl-γ-valerolactone; L-(-)-5-Hexanolide; (S)-(-)-5-Hexanolide
EINECS	Contact for details

Quality Control

Our (S)-5-Hexanolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and excessive heat.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Refractive Index (n20D)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.