Description

3-Hydroxy-3-Methylcyclobutanecarboxylic Acid is a versatile chiral building block featuring a unique cyclobutane ring structure. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials who require high-purity, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its rigid cyclobutane core for enhanced biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers with unique thermal and mechanical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex organic frameworks and as a ligand in asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate for creating novel aroma chemicals with specific stereochemical profiles.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control laboratories.

Basic Information

Product Name	3-Hydroxy-3-Methylcyclobutanecarboxylic Acid
CAS No.	16286-86-5
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	3-Hydroxy-3-methylcyclobutanecarboxylic acid; 3-Methyl-3-hydroxycyclobutanecarboxylic acid; 3-Hydroxy-3-methyl-1-cyclobutanecarboxylic acid; HMCA; (3-Hydroxy-3-methylcyclobutyl)formic acid; 1-Carboxy-3-hydroxy-3-methylcyclobutane
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-3-Methylcyclobutanecarboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets your specific research or production requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.