Description

5-Bromo-2-Methoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and methoxy substituents, which enable selective functionalization for constructing complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Scale-Up: A fundamental substrate for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for clients.

Basic Information

Product Name	5-Bromo-2-Methoxypyridine
CAS No.	16273-54-4
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	2-Methoxy-5-bromopyridine; 5-Bromo-2-pyridinol methyl ether; 5-Bromo-2-methoxypyridine; 2-Methoxypyridine, 5-bromo-; 5-Brom-2-methoxypyridin; 5-Bromo-2-methoxypyridin
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.