Description

Propargyl p-Toluenesulfonate is a specialized organic sulfonate ester, widely recognized as a versatile building block and alkylating agent in advanced chemical synthesis. Its core value lies in its ability to introduce the propargyl group, a key functional handle for further transformations like click chemistry, into target molecules under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients, polymers, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring propargyl ether or ester linkages.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties, including conductive materials.
• Organic Synthesis & Click Chemistry: An essential reagent for introducing alkyne (propargyl) functional groups, enabling efficient Huisgen cycloaddition (click) reactions for bioconjugation and labeling.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Utilized in the multistep synthesis of complex fragrance, flavor, and dye intermediates.

Basic Information

Product Name	Propargyl p-Toluenesulfonate
CAS No.	16192-07-7
Molecular Formula	C10H10O3S
Molecular Weight	210.25 g/mol
Synonyms	Propargyl Tosylate; p-Toluenesulfonic Acid Propargyl Ester; 4-Methylbenzenesulfonic Acid 2-Propynyl Ester; 2-Propynyl p-Toluenesulfonate; Propargyl 4-Toluenesulfonate; Propargyl Tos; Tosyl Propargyl Ester; 4-Toluenesulfonyl Propargyl Ester
EINECS	Contact for details

Quality Control

Our Propargyl p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.