Description

(4As)-4,4A,5,6,8Aα,9-Hexahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-6-One is a high-purity, complex organic compound belonging to the class of substituted naphthofurans. This specialized intermediate is valued for its unique stereochemistry and functional group arrangement, making it a critical building block in advanced organic synthesis. It is primarily sought by research institutions and pharmaceutical development companies for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in complex molecule synthesis.
• Organic Synthesis Building Block: Used in advanced multi-step synthesis for constructing complex polycyclic frameworks in academic and industrial R&D.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies exploring new catalytic methodologies due to its defined stereocenters.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a specific naphthofuran backbone with precise stereochemistry.
• Material Science Research: Investigated as a potential precursor for organic electronic materials or liquid crystals, leveraging its rigid, fused-ring structure.

Basic Information

Product Name	(4As)-4,4A,5,6,8Aα,9-Hexahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-6-One
CAS No.	16148-24-6
Molecular Formula	C₁₇H₂₂O₂
Molecular Weight	258.36 g/mol
Synonyms	4,4a,5,6,8aα,9-Hexahydro-3,4aβ,5β-trimethylnaphtho[2,3-b]furan-6-one; (4aS,5R,8aR)-4,4a,5,6,8a,9-Hexahydro-3,4a,5-trimethylnaphtho[2,3-b]furan-6-one; 3,4aβ,5β-Trimethyl-4,4a,5,6,8aα,9-hexahydronaphtho[2,3-b]furan-6-one; Naphtho[2,3-b]furan-6-one, 4,4a,5,6,8a,9-hexahydro-3,4a,5-trimethyl-, (4aS,5R,8aR)-; NSC 163063
EINECS	Contact for details

Quality Control

Our (4As)-4,4A,5,6,8Aα,9-Hexahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-6-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Optical Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.