Description

Dimethyl Aminomalonate Hydrochloride is a versatile organic salt widely used as a key synthetic intermediate in pharmaceutical and fine chemical manufacturing. Its primary value lies in its bifunctional structure, which allows for the controlled introduction of both amino and ester groups into complex molecules. This compound is essential for researchers and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of amino acids, peptides, and heterocyclic compounds. Its consistent quality and reliable supply are critical for ensuring the reproducibility and scalability of complex synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of non-proteinogenic amino acids, peptide mimetics, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid derivatives.
• Peptide Chemistry: Serves as a protected glycine equivalent or a scaffold for introducing modified amino acid residues into peptide chains.
• Fine Chemical Manufacturing: Employed in the creation of complex organic molecules, chiral auxiliaries, and ligands for asymmetric catalysis.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and bioactive compound libraries.
• Chemical Biology: Used to incorporate stable isotope labels or fluorescent tags into biomolecules for analytical and diagnostic applications.

Basic Information

Product Name	Dimethyl Aminomalonate Hydrochloride
CAS No.	16115-80-3
Molecular Formula	C5H10ClNO4
Molecular Weight	183.59 g/mol
Synonyms	Aminomalonic Acid Dimethyl Ester Hydrochloride; Dimethyl Aminomalonate HCl; Dimethyl 2-Aminomalonate Hydrochloride; 2-Amino-1,3-propanedioic Acid Dimethyl Ester Hydrochloride; Aminomalonic Acid Dimethyl Ester Hydrochloride Salt; Methyl Aminomalonate Hydrochloride; DMAM-HCl; Dimethyl Amino Malonate Hydrochloride
EINECS	Contact for details

Quality Control

Our Dimethyl Aminomalonate Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, residual solvent analysis, and identification by IR and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.