Description

2-(Adamantan-1-Yl)-2-Oxoacetic Acid, also known as 2-(1-Adamantyl)-2-oxoethanoic acid, is a high-value, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. This compound matters because its unique rigid, lipophilic adamantane core combined with a reactive keto-acid functionality enables the development of novel materials and bioactive molecules with enhanced stability and performance. Pharmaceutical, agrochemical, and advanced material research laboratories need this specialized intermediate for synthesizing potential drug candidates, ligands, and polymers where structural robustness and precise functionalization are paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates leveraging the adamantane scaffold.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the adamantane group can impart metabolic stability and unique mode of action.
• Material Science: Building block for high-performance polymers, dendrimers, and metal-organic frameworks (MOFs) requiring rigid, three-dimensional structural components.
• Ligand and Catalyst Development: Serves as a backbone for designing specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Essential reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Specialty Fine Chemicals: Intermediate for producing custom-designed molecules for electronics, coatings, and other high-tech applications.

Basic Information

Product Name	2-(Adamantan-1-Yl)-2-Oxoacetic Acid
CAS No.	16091-98-8
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	2-(1-Adamantyl)-2-oxoethanoic Acid; 2-Adamantyl-2-oxoacetic Acid; 1-Adamantylglyoxylic Acid; Adamantane-1-carboxylic acid, 2-oxo-; 2-Oxo-2-(tricyclo[3.3.1.1³,⁷]dec-1-yl)acetic acid; 16091-98-8; NSC 163082
EINECS	Contact for details

Quality Control

Our 2-(Adamantan-1-Yl)-2-Oxoacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.