Description

7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid is a high-purity, functionalized benzodioxine derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. Pharmaceutical researchers, agrochemical developers, and material scientists need this intermediate for its unique bromine and carboxylic acid functionalities, which enable precise chemical modifications for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the benzodioxine core for biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors and advanced polymers due to its electron-rich aromatic system.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic Acid
CAS No.	16081-71-3
Molecular Formula	C9H7BrO4
Molecular Weight	259.06 g/mol
Synonyms	5-Bromo-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid; 7-Bromo-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid; 7-Bromo-2,3-dihydrobenzo-1,4-dioxine-5-carboxylic acid; 6-Carboxy-5-bromo-2,3-dihydro-1,4-benzodioxin; 7-Bromo-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid; 16081-71-3; 7-Bromodihydrobenzo-1,4-dioxine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.