Description

5-Hydroxy-2-(Iodomethyl)-4H-Pyran-4-One is a versatile iodinated pyranone derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both a reactive iodomethyl group and a hydroxylated pyranone core, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those requiring halogenated heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the iodine atom can be leveraged for further functionalization.
• Fine Chemical Building Block: Employed in the preparation of complex organic molecules for material science, dyes, and specialty chemicals.
• Cross-Coupling Reactions: The iodomethyl group makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	5-Hydroxy-2-(Iodomethyl)-4H-Pyran-4-One
CAS No.	16065-34-2
Molecular Formula	C6H5IO3
Molecular Weight	251.01 g/mol
Synonyms	5-Hydroxy-2-(iodomethyl)-4H-pyran-4-one; 2-(Iodomethyl)-5-hydroxy-4H-pyran-4-one; 4H-Pyran-4-one, 5-hydroxy-2-(iodomethyl)-; Kojic acid iodomethyl derivative; Iodomethyl kojic acid; 5-Hydroxy-2-iodomethyl-γ-pyrone
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-(Iodomethyl)-4H-Pyran-4-One is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.