Description

[1R-(1Alpha,2Beta,5Alpha)]-2-(Isopropyl)-5-Methylcyclohexanecarboxylic Acid is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its precise stereochemistry makes it a valuable building block for the production of complex molecules where spatial orientation is critical for biological activity or material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, anti-inflammatory agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence the efficacy and environmental profile of the final product.
• Flavor & Fragrance Ingredient: Serves as a precursor in the synthesis of high-value aroma chemicals and flavoring agents, leveraging its terpene-like structural motif.
• Ligand & Catalyst Development: Employed in academic and industrial research for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or building block in the development of specialized polymers and liquid crystals with tailored optical or mechanical properties.

Basic Information

Product Name	[1R-(1Alpha,2Beta,5Alpha)]-2-(Isopropyl)-5-Methylcyclohexanecarboxylic Acid
CAS No.	16052-40-7
Molecular Formula	C11H20O2
Molecular Weight	184.28 g/mol
Synonyms	(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanecarboxylic acid; (1R,2S,5R)-Menthoxyacetic acid precursor; (-)-Menthylacetic acid derivative; (1R,2S,5R)-2-(1-Methylethyl)-5-methylcyclohexanecarboxylic acid; L-Menthone related acid; Stereoisomer of p-menthane-1-carboxylic acid; Chiral cyclohexanecarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,2Beta,5Alpha)]-2-(Isopropyl)-5-Methylcyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.