Description

3-Chlorocyclobutanemethanol is a versatile chlorinated cyclobutane derivative that serves as a valuable chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a reactive chloromethyl group and a strained cyclobutane ring, makes it a critical precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for novel polymers and specialty materials with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and reference standards.

Basic Information

Product Name	3-Chlorocyclobutanemethanol
CAS No.	15963-47-0
Molecular Formula	C5H9ClO
Molecular Weight	120.58 g/mol
Synonyms	(3-Chlorocyclobutyl)methanol; 3-Chlorocyclobutan-1-ylmethanol; Cyclobutanemethanol, 3-chloro-; 1-(Chloromethyl)-3-hydroxycyclobutane; 3-Chloro-1-cyclobutanemethanol
EINECS	Contact for details

Quality Control

Our 3-Chlorocyclobutanemethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, chiral purity (if applicable), and identity confirmation (IR, NMR). A detailed Certificate of Analysis (COA) is supplied with each batch, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.