Description

(E)-2-Bromo-3-Phenyl-2-Propen-1-Oic Acid CAS NO 15894-30-1 is a high-purity, synthetically valuable α,β-unsaturated carboxylic acid derivative featuring a bromine substituent. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions, Michael additions, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a functionalized cinnamic acid backbone.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Used in Heck coupling, Suzuki-Miyaura coupling, and other palladium-catalyzed cross-coupling reactions to introduce the phenylpropenoic acid moiety.
• Material Science Research: Monomer or precursor for synthesizing specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Potential use in designing activity-based probes or affinity tags due to its electrophilic alkene and carboxylic acid functional groups.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	(E)-2-Bromo-3-Phenyl-2-Propen-1-Oic Acid
CAS No.	15894-30-1
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	(E)-2-Bromocinnamic Acid; trans-2-Bromocinnamic Acid; 2-Bromo-3-phenylacrylic Acid; (E)-3-Phenyl-2-bromoacrylic Acid; β-Bromocinnamic Acid; NSC 403697; (E)-α-Bromocinnamic Acid; 2-Bromocinnamic Acid (trans)
EINECS	Contact for details

Quality Control

Our (E)-2-Bromo-3-Phenyl-2-Propen-1-Oic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.