Description

2,3-Dihydro-1H-Indole-5-Carboxylic Acid is a versatile indoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its fused bicyclic structure, which provides a privileged scaffold for constructing complex molecules with biological activity. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and inflammation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or building block for novel polymers, dyes, and organic electronic materials.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2,3-Dihydro-1H-Indole-5-Carboxylic Acid
CAS No.	15861-30-0
Molecular Formula	C9H9NO2
Molecular Weight	163.18 g/mol
Synonyms	5-Indolinecarboxylic Acid; Indoline-5-carboxylic Acid; 2,3-Dihydro-1H-indole-5-carboxylic acid; 5-Carboxyindoline; 1,2,3,4-Tetrahydro-5-isoquinolinecarboxylic acid (related structure); 5-Indolincarboxylic acid
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Indole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of moisture from the atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.