Description

5-Chloro-2-Ethoxyaniline is a versatile aromatic amine intermediate of significant importance in advanced organic synthesis. Its value lies in its dual functional groups—the chloro and ethoxy substituents on the aniline ring—which allow for selective chemical transformations and the construction of complex molecular architectures. This compound is primarily needed by manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients, dyes, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aromatic amine backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where its substituted aniline structure serves as a core moiety.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other colorants, contributing to color fastness and specific hue properties.
• Organic Synthesis Reagent: Employed in research and development for coupling reactions, such as Buchwald-Hartwig amination, to create novel compounds.
• Polymer Additive: Can be utilized in the production of specialty polymers and resins as a curing agent or modifier.
• Chemical Research: A valuable standard and starting material in academic and industrial laboratories for methodological studies and new molecule discovery.

Basic Information

Product Name	5-Chloro-2-Ethoxyaniline
CAS No.	15793-48-3
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	2-Amino-4-chlorophenetole; 4-Chloro-2-ethoxyaniline; 2-Ethoxy-5-chloroaniline; 5-Chloro-2-phenetidine; 1-Amino-2-ethoxy-5-chlorobenzene; Benzenamine, 5-chloro-2-ethoxy-; 2-Ethoxy-5-chlorobenzenamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxyaniline is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the rigorous standards required for pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.