Description

3-Methylenecyclobutanecarboxylic Acid is a specialized, high-value carboxylic acid derivative featuring a strained cyclobutane ring with an exocyclic methylene group. This unique molecular architecture makes it a versatile and reactive synthon for advanced organic synthesis and pharmaceutical research. It is particularly sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing constrained ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with unique modes of action.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: The carboxylic acid and alkene functionalities provide handles for creating novel chelating ligands and organometallic catalysts.
• Material Science Research: Investigated for the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cycloaddition and ring-opening reactions.

Basic Information

Product Name	3-Methylenecyclobutanecarboxylic Acid
CAS No.	15760-36-8
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	3-Methylenecyclobutanecarboxylic Acid; 3-Methylene-1-cyclobutanecarboxylic Acid; Cyclobutane-1-carboxylic acid, 3-methylene-; 3-Methylencyclobutan-1-carbonsäure (German); Acide 3-méthylènecyclobutanecarboxylique (French); 3-Methylenecyclobutanecarboxylic acid (15760-36-8)
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and production use. Our standard offering for 3-Methylenecyclobutanecarboxylic Acid typically meets a purity specification of ≥95% (by HPLC or GC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and can tailor purity grades to meet specific project requirements under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend maintaining the product at 2-8°C under an inert atmosphere to preserve stability and prevent potential degradation or polymerization. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.