Description

5-tert-Butyl-2-Methylthiophenol is a specialized aromatic thiol compound, recognized for its unique sterically hindered phenolic structure. This compound matters as a versatile and critical building block in advanced organic synthesis, offering a reactive thiol group and a bulky tert-butyl substituent that influences reaction pathways and product stability. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for applications ranging from ligand synthesis to polymer modification and as a precursor for antioxidants.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the production of active pharmaceutical ingredients (APIs), particularly those requiring hindered phenolic or thioether functionalities.
• Agrochemical Synthesis: Used in the manufacture of pesticides, herbicides, and fungicides where its structural motif can contribute to biological activity and stability.
• Polymer Additive & Modifier: Acts as a chain transfer agent, antioxidant precursor, or cross-linking agent in the synthesis and stabilization of specialty polymers and rubbers.
• Ligand for Catalysis: Employed in the development of metal-chelating ligands for homogeneous catalysis, leveraging the sulfur donor atom.
• Organic Synthesis Building Block: A valuable reagent for introducing the tert-butyl-2-methylthiophenyl group into more complex molecular architectures.
• Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	5-tert-Butyl-2-Methylthiophenol
CAS No.	15570-10-2
Molecular Formula	C11H16S
Molecular Weight	180.31 g/mol
Synonyms	2-Methyl-5-tert-butylbenzenethiol; 5-tert-Butyl-2-methylbenzenethiol; 2-(1,1-Dimethylethyl)-6-methylbenzenethiol; 2-Methyl-5-(tert-butyl)thiophenol; 5-tert-Butyl-o-thiocresol; 2-Mercapto-4-tert-butyltoluene; 4-tert-Butyl-2-methylbenzenethiol; 15570-10-2
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-2-Methylthiophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting compliance with internal and regulatory specifications for advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. Due to the presence of the thiol group, consider storing under an inert atmosphere for long-term stability to prevent oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.