Description

Di-Lithium Tetrabromocuprate(II) Solution, 0.1 M in THF is a specialized organometallic reagent, specifically a lithium cuprate complex, prepared as a standardized solution in tetrahydrofuran. This product is valued for its role as a highly effective nucleophilic copper reagent in organic synthesis, enabling critical carbon-carbon bond-forming reactions. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable reagents for complex synthetic transformations.

Application

• Conjugate (1,4-) Addition Reactions: A premier reagent for the Michael addition of nucleophiles to α,β-unsaturated carbonyl compounds, ketones, and nitriles.
• Cross-Coupling Reactions: Used in copper-mediated coupling with organic halides or pseudohalides for the formation of C-C bonds.
• Synthetic Intermediate: Serves as a key intermediate in the multi-step synthesis of complex natural products, active pharmaceutical ingredients (APIs), and fine chemicals.
• Polymer Chemistry: Employed in the synthesis and modification of polymers and advanced materials requiring specific copper-mediated linkages.
• Catalyst Precursor: Acts as a precursor for generating active copper catalysts in situ for various organic transformations.
• Asymmetric Synthesis: When used with chiral ligands, it can facilitate enantioselective addition reactions for the production of chiral molecules.

Basic Information

Item	Details
Product Name	Di-Lithium Tetrabromocuprate(II) Solution, 0.1 M in THF
CAS No.	15489-29-9
Molecular Formula	CuBr4Li2
Molecular Weight	374.19 g/mol (for CuBr4Li2)
Synonyms	Lithium Tetrabromocuprate(II); Lithium Cuprate(II) Bromide; Tetrabromocuprate(2-) Dilithium; Copper Lithium Bromide Complex; Cuprate Reagent, 0.1M in THF; Li2CuBr4; Dilithium Tetrabromocuprate
EINECS	Contact for details

Quality Control

Every batch of our Di-Lithium Tetrabromocuprate(II) Solution is manufactured and analyzed under strict quality protocols to ensure consistency and reliability for sensitive synthetic applications. We guarantee precise molarity and high chemical purity, with rigorous testing for moisture content and metallic impurities. A comprehensive Certificate of Analysis (COA) detailing assay, identity, and solvent purity is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) to maintain stability and potency. The solution is highly volatile (THF solvent) and easily oxidized; ensure containers are securely sealed and handled in a well-ventilated area. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Clear, dark brown to black solution
Concentration	0.1 M in THF
Assay (Cuprate Content)	≥ 95% (by titration)
Identification (IR)	Conforms to reference
Water Content (Karl Fischer)	< 100 ppm
THF Purity (GC)	≥ 99.8%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.