Description

Kaempferol-3,7,4'-Trimethyl Ether is a specific, methylated derivative of the flavonoid kaempferol. This chemical modification enhances its stability and alters its physicochemical properties, making it a valuable reference standard and a key intermediate for advanced research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and life science sectors who require high-purity, well-characterized compounds for analytical, biological, and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity assessment, and quantification of related flavonoid compounds in drug development and quality control.
• Biochemical Research: Serves as a key intermediate or probe in studying the structure-activity relationships (SAR) of flavonoid derivatives, particularly their antioxidant, anti-inflammatory, or other biological effects.
• Nutraceutical & Cosmetic Ingredient Research: Investigated as a potential active ingredient or a precursor for developing stable, bioavailable formulations in dietary supplements and personal care products.
• Chemical Synthesis: Acts as a protected or functionalized building block for the semi-synthesis of novel flavonoid analogs with tailored properties.
• Analytical Chemistry: Employed in method development and validation for chromatographic techniques (HPLC, LC-MS) aimed at detecting and measuring flavonoids in complex matrices.

Basic Information

Product Name	Kaempferol-3,7,4'-Trimethyl Ether
CAS No.	15486-34-7
Molecular Formula	C₁₈H₁₆O₆
Molecular Weight	328.32 g/mol
Synonyms	3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one 3,7-dimethyl ether; Kaempferol 3,7,4'-trimethyl ether; 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5-hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-; 3,7,4'-Tri-O-methylkaempferol; Kumatakenin (Note: Verify synonym applicability); 3,5-Dihydroxy-7,4'-dimethoxyflavone 3-methyl ether
EINECS	Contact for details

Quality Control

Our Kaempferol-3,7,4'-Trimethyl Ether is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.