Description

4-(Trimethylsilyl)Benzoic Acid is a high-purity organosilicon derivative of benzoic acid, serving as a versatile building block in advanced organic synthesis. Its unique structure, featuring a trimethylsilyl-protecting group ortho to a carboxylic acid, makes it a critical intermediate for modifying molecular properties and enabling complex coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting specific receptor sites.
• Liquid Crystal & OLED Material Synthesis: Used in the production of advanced organic electronic materials and liquid crystal displays (LCDs) due to its ability to modify molecular conformation and electronic properties.
• Agrochemical Active Ingredient Development: Serves as a precursor in the synthesis of new-generation herbicides, fungicides, and plant growth regulators.
• Polymer Modification Agent: Incorporated into polymer chains to impart specific characteristics such as altered solubility, thermal stability, or surface properties.
• Organic Synthesis Reagent: Acts as a protected benzoic acid derivative in multi-step synthetic routes, including Suzuki-Miyaura and other cross-coupling reactions.
• Surface Chemistry & Silane Coupling Agent Research: Utilized in studies of surface modification, adhesion promotion, and the creation of self-assembled monolayers (SAMs).

Basic Information

Product Name	4-(Trimethylsilyl)Benzoic Acid
CAS No.	15290-29-6
Molecular Formula	C10H14O2Si
Molecular Weight	194.30 g/mol
Synonyms	4-(Trimethylsilyl)benzoic acid; Benzoic acid, 4-(trimethylsilyl)-; p-(Trimethylsilyl)benzoic Acid; 4-Carboxybenzenetrimethylsilane; 4-TMS-benzoic acid; (4-Carboxyphenyl)trimethylsilane; p-Trimethylsilylbenzoic Acid; 15290-29-6
EINECS	Contact for details

Quality Control

Every batch of 4-(Trimethylsilyl)Benzoic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	155°C - 160°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.