Description

m-Bromocinnamaldehyde is a versatile aromatic aldehyde building block featuring a bromine substituent on the meta position of the cinnamaldehyde scaffold. This compound matters for its dual functionality, serving as a key electrophile in cross-coupling reactions and a reactive aldehyde for condensation chemistry, enabling the synthesis of complex heterocycles and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting CNS disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced fungicides and herbicides, leveraging its halogenated structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display technologies.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine and N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Flavor and Fragrance Chemistry: Acts as a starting material for the synthesis of complex aroma chemicals and fragrance molecules.
• Academic and Industrial Research: A valuable reagent for methodological development in cross-coupling (e.g., Suzuki, Heck) and heterocycle formation reactions.
• Polymer Modification: Used to introduce aromatic and reactive aldehyde functionalities into polymer backbones for specialty materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme activity and protein interactions.

Basic Information

Product Name	m-Bromocinnamaldehyde
CAS No.	15185-59-8
Molecular Formula	C9H7BrO
Molecular Weight	211.06 g/mol
Synonyms	3-Bromocinnamaldehyde; (E)-3-(3-Bromophenyl)acrylaldehyde; 3-Bromobenzylideneacetaldehyde; m-Bromobenzylideneacetaldehyde; (E)-3-(3-Bromophenyl)-2-propenal; 3-Bromocinnaldehyde; trans-3-Bromocinnamaldehyde; 2-Propenal, 3-(3-bromophenyl)-, (E)-
EINECS	Contact for details

Quality Control

Our m-Bromocinnamaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure compliance with exacting industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. For customers requiring specific grade certifications (e.g., for pharmaceutical development), please contact our technical sales team to discuss custom synthesis and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.